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@amathislab

Mathis Group @ EPFL

Computational Neuroscience and AI

Welcome to the A. Mathis Group at EPFL!

Broadly speaking, we work at the intersection of computational neuroscience and machine learning, aka AI4(Neuro)Science. Ultimately, we are interested in reverse-engineering the algorithms of the brain, in order to figure out how the brain works and to build better artificial intelligence systems. We are also interested in understanding the principles of behavior, and thus work actively on ways to measure it.

Check out group's website for more information, and see our open source code below!

We also share open data/model weights on Zenodo and Huggingface!

Software packages for behavioral analysis:

  • DeepLabCut: for animal pose estimation
  • DLC2action: for action segmentation
  • hBehaveMAE: unsupervised action decomposition for hierarchical behavior
  • LLaVAction: multimodal language model for action recognition

Code from winning ML competitions:

Skill learning (MyoChallenges @NeurIPS):

Selected Code from published research projects 👩‍💻:

Computer Vision and Behavioral Analysis:

AI4Science including modeling proprioception and sensorimotor control:

Reinforcement learning (mostly for motor skills also relevant for modeling sensorimotor control):

Also check out the section on winning MyoChallenges at NeurIPS (in 2022, 2023 and 2025)!

Datasets and benchmarks:

🌈 Please reach out, if you want to work with us! We love collaborative, open-source science.

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  1. Kinesis Kinesis Public

    [ICRA 2026] The official implementation of the paper "Reinforcement Learning-Based Motion Imitation for Physiologically Plausible Musculoskeletal Motor Control"

    Python 154 26

  2. BUCTD BUCTD Public

    [ICCV 2023] Rethinking pose estimation in crowds: overcoming the detection information-bottleneck and ambiguity

    Python 103 14

  3. lattice lattice Public

    [NeurIPS 2023] Latent Exploration for Reinforcement Learning

    Python 49 5

  4. Task-driven-Proprioception Task-driven-Proprioception Public

    Forked from amathislab/DeepDraw

    [Cell 2024]: Code for Task-driven neural network models predict neural dynamics of proprioception by Marin Vargas* and Bisi* et al.

    Jupyter Notebook 20

  5. HOISDF HOISDF Public

    [CVPR 2024] HOISDF: Constraining 3D Hand-Object Pose Estimation with Global Signed Distance Fields

    Python 84 3

  6. musclemimic musclemimic Public

    Official repo of Towards Embodied AI with MuscleMimic: Unlocking full-body musculoskeletal motor learning at scale

    Python 363 51

Repositories

Showing 10 of 53 repositories
  • musclemimic_models Public

    Musculoskeletal models released from musclemimic research: fullbody musculoskeletal model

    amathislab/musclemimic_models's past year of commit activity
    Python 63 Apache-2.0 7 0 0 Updated Oct 30, 2026
  • soma Public
    amathislab/soma's past year of commit activity
    0 Apache-2.0 0 1 0 Updated Oct 30, 2026
  • mm-evalkit Public

    Evaluating musclemimic policies with neuroscience lab data

    amathislab/mm-evalkit's past year of commit activity
    Python 9 Apache-2.0 0 0 1 Updated Oct 29, 2026
  • arnold Public

    Arnold: A generalist muscle transformer policy

    amathislab/arnold's past year of commit activity
    Python 19 1 1 0 Updated Oct 27, 2026
  • myochallenge Public

    [NeurIPS 2022, Neuron 2024] Winning code for the Baoding ball MyoChallenge at NeurIPS 2022

    amathislab/myochallenge's past year of commit activity
    Python 23 MIT 1 1 0 Updated Oct 20, 2026
  • MyoChallengeAnalysis Public

    [Neuron 2024] Analysis of Baoding ball policy from MyoChallenge at NeurIPS 2022

    amathislab/MyoChallengeAnalysis's past year of commit activity
    Jupyter Notebook 7 MIT 0 0 0 Updated Oct 20, 2026
  • DeepDraw Public

    [eLife 2023] Code for "Contrasting action and posture coding with hierarchical deep neural network models of proprioception"

    amathislab/DeepDraw's past year of commit activity
    Jupyter Notebook 17 MIT 2 0 0 Updated Oct 20, 2026
  • Task-driven-Proprioception Public Forked from amathislab/DeepDraw

    [Cell 2024]: Code for Task-driven neural network models predict neural dynamics of proprioception by Marin Vargas* and Bisi* et al.

    amathislab/Task-driven-Proprioception's past year of commit activity
    Jupyter Notebook 20 MIT 2 0 0 Updated Oct 20, 2026
  • musclemimic Public

    Official repo of Towards Embodied AI with MuscleMimic: Unlocking full-body musculoskeletal motor learning at scale

    amathislab/musclemimic's past year of commit activity
    Python 363 Apache-2.0 51 1 1 Updated Oct 20, 2026
  • terra Public

    Official code implementation of "TERRA: Terrain-Aware Reconstruction, Retargeting and Control for Musculoskeletal Locomotion"

    amathislab/terra's past year of commit activity
    Python 161 Apache-2.0 14 1 0 Updated Oct 18, 2026

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